HCA Capital Division
7300 Beaufont Springs Rd, Suite 101
Richmond, VA 23225
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The Prostate Cancer Risk Profiler is based on published guidelines, articles, and a statistical model from the Prostate Cancer Prevention Trial.
The Prostate Cancer Risk Profiler uses American Cancer Society recommendations to suggest whether or not you should have your prostate-specific antigen (PSA) tested and how often based on your previous PSA results, age, immediate family history, and ethnicity. The decision about whether or not to have a PSA test done should be discussed with your health care provider.
The Prostate Cancer Risk Profiler also assesses some of the most common risk factors and protective factors for prostate cancer. These factors include:
This profiler is intended only for men who have NOT already been diagnosed with prostate cancer. The results of this profiler are based on widely accepted research, but are only accurate for the intended audience.
Can't answer all of the questions? No problem. The Result Report will still have valuable information for you. When finished, print and share your Result Report with your doctor.
The risk estimates for prostate cancer and high-risk prostate cancer are based on the Prostate Cancer Risk Calculator from the Prostate Cancer Prevention Trial. The results show both your percent chance of having a biopsy-detectable prostate cancer, as well as a high-grade prostate cancer. High grade prostate cancer risk is the chance of having a more aggressive cancer that spreads outside the prostate gland possibly requiring more aggressive treatment.
Current Risk of Prostate Cancer
The Current Risk of prostate cancer is calculated from an equation that includes your immediate family history of prostate cancer, your PSA test level, your digital rectal exam result, and if you previously had a prostate biopsy.1 Patients are flagged for being at High Risk if the Current Prostate Cancer Risk is greater than 25%. This may represent a number at which further tests may be considered.
High-grade Risk of Prostate Cancer
High-grade Cancer Risk includes the same risk factors included in the Current Risk of prostate cancer. However, it also factors in your current age and whether or not you are African American.1 High-grade prostate cancer is defined as Gleason Score greater than or equal to 7. The Gleason Score is determined from a biopsy and it tells you how likely it is that a cancer has spread outside the prostate gland.
The Prostate Cancer Prevention Trial2 also showed that PSA levels are lower in overweight and obese men. The Current and High-grade risk calculations in the Prostate Cancer Risk Profiler use adjusted PSA levels.
95% Confidence Interval
No estimate is perfect and the 95% confidence interval reflects the uncertainty by giving a range of risks that would be correct 95 percent of the time. Interpret your risk of cancer as the possibility that the actual number would fall somewhere within this range 95% of the time.
The risk estimates are only applicable to men who:
The risk estimate does not reflect an endorsement of either PSA or DRE for screening for prostate cancer. Also, no specific level of risk is recommended for prostate biopsy and this decision should be an individual choice based upon a provider-patient relationship.References
Early Prostate Cancer in Immediate Family
Having a father or brother with prostate cancer more than doubles a man's risk of developing this disease. The risk is much higher for men with several affected relatives, particularly if their relatives were younger than age 65 at the time the cancer was found.
Sometimes people don't have much information about the health and medical problems in their extended family. It's a good idea to ask family members about their medical history and to write it down for future reference.
If you don't know your family's medical history today, complete the questions as best you can but come back later once you've had a chance to ask your relatives for their histories.